CIN '2007 - 4th CONGRESS OF NEPHROLOGY IN INTERNET
Analysis and Redesign of a Knowledge Database for a Drug-Drug Interactions Alert System
Dr. Daniel Luna
Department of Medical Informatics, Hospital Italiano de Buenos Aires, Argentina
Abstract
Physicians tend to ignore drug-drug interactions alerts, this is due to the great amount of irrelevant interactions displayed and the interface in which these alerts are shown. The high rate of clinically inadequate alerts produce “alerts fatigue”. This high number of incorrect alerts predisposes physicians to underestimate the electronic prescription systems as useful tools in their practice. We decided to analyze and redesign our drug-drug interactions alerting system knowledge database. In order to do so, we proceeded to clean our knowledge database accordingly to the clinical significance of drug-drug interac-tions. A new drug interactions taxonomy was created based on the recommendations given in each single monograph of inter-action. Finally we proceeded to recategorize the alerts as Ac-tive or Passive whether if they needed to be intrusive in the prescribing process or not.Comments: