CIN '2007 - 4th CONGRESS OF NEPHROLOGY IN INTERNET

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Cellular mechanisms behind the increased CV risk in dialysis patients

Andréa E. M. Stinghen and Roberto Pecoits-Filho

Center for Health and Biological Sciences, Pontifícia Universidade Católica do Paraná, Curitiba, PR

Abstract

There has recently been much interest in the mechanisms whereby chronic kidney disease (CKD) could promote an increased risk of cardiovascular disease (CVD) . Patients with CKD present a broad array of traditional and emerging non-traditional risk factors for cardiovascular disease , but specific mechanisms mediating the enhanced risk for CVD are not well defined . The central mechanisms involved in this process have shifted recently to include inflammation as a pivotal factor determining the progression of atherosclerosis (Fig. 1).

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