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Do ultrasound renal resistance indices reflect systemic or renal vascular damage in chronic kidney disease?

Dr Gunnar H Heine

Medical Department, Nephrology, University Homburg, Homburg,

Abstract

Several recent studies suggested that elevated renal resistance indices measured by Duplex ultrasound predict the future progression of renal disease . In the largest of these studies, Radermacher and coworkers reported a resistance index value of  0.80 to be an independent risk factor for progression of kidney disease and death in patients suffering from chronic renal disease even after adjustment for arterial hypertension, renal function and proteinuria . Similarly, the same authors reported that ultrasound renal resistive index 0.80 independently predicted an unfavorable outcome in kidney transplant patients . Nevertheless, most clinicians currently rely on measurements of blood pressure, proteinuria and glomerular filtration rate rather than on ultrasound studies when predicting future progression of chronic kidney disease in individual patients.

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